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Supplemental Technology Award Review System (STARS)

Overview

STARS Request Form STARS System

The Supplemental Technology Award Review System (STARS) is a web-based interface for submission and review of requests from CCR PIs for one-time supplements for experimental cost in support of ongoing activities.  
 
What is STARS, and how does it relate to OSTR subsidies and RRS?
 
  • STARS is not a means to launch new projects. High-impact new projects should ideally be prioritized in the PI’s core allocation or should be submitted to the FLEX Program.  Equipment requests, meeting requests, and animal resource requests will continue to be considered in RRS. (CCR Supplemental Funding Resources)
  • Requests for supplementary experimental costs related to ongoing work can be submitted through STARS.  Requests for additional S&S, expansion of S&S or restoration of S&S are not considered in STARS. 
  • Submission is on a rolling basis without specific due dates or calls for proposals.
  • Award amounts are flexible.  Although there is no upper limit, most requests do not exceed $20,000. Please note that only PIs may submit supplement requests in excess of $10,000.  Budgets should be very well-justified, linked to specific project-related expenses, and include appropriate PI co-funding.
  • Eligible expenses include services from dedicated cores and outside vendors (e.g., custom antibody development, protein production/purification, metabolomics profiling, DNA and RNA sequencing, genomic profiling, methylation analysis, etc.).
  • All project-associated costs for STARS awards, regardless of amount, will be reimbursed to PI accounts upon demonstration of proof of purchase (instructions to obtain reimbursement will be provided in an email upon request approval).  All awards must be used within 90 days of approval.
  • Requests for supplements of up to $10,000 are reviewed for technical merit by OSTR until a PI reaches the $10,000 OSTR supplement limit.  Requests for supplements of greater than $10,000 are evaluated on a rolling basis by members of the CCR Science Board (CSB) using the STARS Review Criteria: 
    • STARS ​is designed to support ongoing activities, not to initiate new projects or develop new directions of ongoing projects. Requests for seed funding for new projects/new directions should be directed to FLEX or other appropriate funding mechanism(s).
    • Since STARS is designed to support ongoing activities, there should be strong evidence of feasibility and an indication that milestones will be reached. STARS projects should not be exploratory.
    • If a large-scale, ongoing effort requires larger amounts of support and will yield important results, it is appropriate to be considered in STARS. However, the higher the request amount the more exceptional the science and impact must be.
    • The requested resources should be well-justified and clearly required to carry out the proposed work. The experimental design should be appropriate to the research question(s) being addressed; the cost elements for the proposed work should be sufficiently broken out so that the accuracy of the total request can be verified; an appropriate level of commitment of the PI’s base budget should be evident.
  • STARS outcome notifications will include summary evaluations.  Resubmissions are allowed but must be responsive to reviewer evaluations.
  • Funds for the STARS program are limited and will be allocated and distributed evenly throughout the fiscal year.
  • Please carefully read the STARS submission instructions before entering your request.

STARS Submission Instructions

How do I use my Supplemental Technology Award? 

Requests over $10,000:  For projects requiring technology supplements in excess of $10,000, the STARS Request Form  will ask for a detailed scientific and budgetary justification, as well as information on the Cores or vendors you will be using. Because the requests are project-based, you may include several cores and vendors in one request. Proposals will be reviewed by members of the CCR Science Board on a rolling (monthly) basis.  Outcome notifications will be emailed and will include comments from reviewers. Note that approved project expenses will be paid directly by CCR OD; funds will NOT be transferred to your budget.

Requests under $10,000:  If you are requesting a supplement of $10,000 or less for CCR-dedicated cores hosted by CRTP, you do NOT need to submit a separate STARS request.  Subsidy amounts for CRTP services are predetermined by service type and will be included in your cost estimate, which you request via the NCI at Frederick Accessioning System
 

CCR-Dedicated cores hosted by CRTP are:

If you are requesting subsidy in any amount for a vendor or core that is NOT one of the CCR-dedicated cores hosted by CRTP, use the STARS request form, to provide basic details of the technology or services you require.  Note that you are required to cover 50% of the total cost from your own laboratory budget and to place your orders directly to the respective companies through the standard procurement process.  In order to be eligible for the subsidy, investigators must fill in and submit the subsidy form PRIOR TO placing the order with the company.  The exceptions to this are when subsidies are requested for services through the CCR Genomics Core, the High Throughput Imaging Facility (HiTIF), and the Collaborative Protein Technology Resource (CPTR).  In these special cases, investigators can submit subsidy request after they have been billed for services.  

Once the subsidy is approved, place the order for the full cost of the purchase against your laboratory CAN or PID.  When the order has been placed and is documented in SOFie or CMS Budget Reports, email Dee Crouse (croused@mail.nih.gov) and Alan Peigh (peigha@od.nci.nih.gov).  OSTR funds will only be transferred in the amount of the approved subsidy to reimburse your laboratory CAN/PID once proof of purchase has been received.

External vendor services can be found through the NIH IRP Collaborative Research Exchange (CREx).

Technologies and services available from outside vendors are also eligible for OSTR subsides.  Please click on the links below to access instructions for obtaining price lists and/or contact information for the companies whose services and technologies are supported by OSTR:

Services and Companies Supported with OSTR Subsidy

Array Platform

Hybridization kits and other ancillary reagents are NOT covered by OSTR subsidies - Affymetrix Arrays/chips are no longer eligible for subsidy.

Agilent

Katherine Fawcett, Genomics Account Manager
Tel: 440-221-0663

Illumina

Rob Genuario, Ph.D., Regional Account Manager
Cell: 240-394-2122
Fax: 301-829-5247

Life Technologies/Applied Biosystems

Christopher Brown, Sr. Sales Representative, Instruments Gene Expression and MicroRNA Quantitation
5781 Van Allen Way
Carlsbad, CA 92008
T: 1-800-327-3002
Cell: 703-967-0586
VM: 1-800-248-0281, x7215

Roche-NimbleGen

James Furbee, Ph.D.
Sequencing Solutions Account Manager
Phone: 919-208-6056

Qiagen/SABiosciences

Jeffrey Durocher, Territory Sales Representative QIAGEN Inc.
19300 Germantown Road
Germantown, MD 20874
Phone: 240-449-5109

Illumina/MiSEQ Sequencing

Affymetrix

Meg Mintz Kelly, Account Manager
NIH and Military Accounts

Fluidigm

Jeff Barnes, Associate Director, Clinical Research and Testing

757-615-4230

Bioinformatics Software

Qlucore

Beth Repetti
Sales Representative
beth.repetti@qlucore.com
Website: http://www.qlucore.com
 
To obtain access to Qlucore Omics Explorer software, please obtain a quotation from Sara Strandberg.  Once a quotation is obtained, please submit a subsidy request for 50% support from OSTR.  Upon subsidy approval, the software must be purchased through your Purchasing Agent using your laboratory CAN or Frederick Project Number.  Once the order has been placed, the subsidy funds will be transferred to your account.

 

 

 

Life Technologies/Oncomine

Kathi Downs
Sr. Inside Sales and Support Specialist
Compendia Bioscience – now part of Life Technologies
110 Miller Avenue
Floor 2
Ann Arbor, MI 48104
USA
 
t (734) 929-3915
f (734) 929-0087
 
 
To obtain access to Oncomine software, please obtain a quotation from Kathi Downs.  Once a quotation is obtained, please submit a subsidy request for 50% support from OSTR.  Upon subsidy approval, the software must be purchased through your Purchasing Agent using your laboratory CAN or Frederick Project Number.  Once the order has been placed, the subsidy funds will be transferred to your account.

Custom and Specialized Antibodies (Eligible for 50% OSTR Subsidy)

Abcam

Sandy Chou, Ph.D
Collaborations Manager
Abcam Burlingame
http://www.abcam.com

Abcam Burlingame
863 Mitten Road Suite 103
Burlingame CA 94010-1303
Tel: 650-583-6688, Ext: 2314
 
The total cost per one rabbit monoclonal antibody is $6678. 50% subsidy will be granted for the development of each antibody. The total amount of subsidy available per principal investigator is not to exceed $6678 (enough to cover production of 2 antibodies). For more information on the production of rabbit monoclonal antibodies, the Epitomics/NCI agreement and how to request a new antibody, please visit Antibody Development.

Rockland Immunochemicals, Inc.

Karin Abarca-Heideman, Ph.D., Director R&D
Phone: 1-610-369-1008 or 1-800-656-7625
 
For each successful polyclonal or monoclonal antibody produced by Rockland and validated by CCR Rockland will deliver to the validating investigators up to five milligrams of each polyclonal collaboration antibody, three milligrams of each monoclonal collaboration antibody and one vial of Rockland antibodies for validation purposes.

Chromotek

Stephanie Dennison, MS
phone: 443-280-0474
email: s.dennison@chromotek.com

Digital Gene Expression Profiling

NanoString

Inna Dzekunova
Regional Project Specialist
Cell: 443-844-0815

Epigenetic Products

Active Motif

1914 Palomar Oaks Way, Suite 150
Carlsbad, CA  92008
Toll Free: 877 222 9543
Direct: 760 431 1263
Fax: 760 431 1351
tech_service@activemotif.com
 
Epigenetics & Chromatin         http://www.activemotif.com/epichrom
Antibodies                               http://www.activemotif.com/abs
Transcriptional Regulation      http://www.activemotif.com/transreg
Epigenetic Services                 http://www.activemotif.com/services

Full Microarray Service (Eligible for 33% OSTR Subsidy)

GenUs Biosystems

Michael Falduto
Phone: 1-847-291-9600
Cell: 1-312-371-5123
Fax: 1-847-291-9903

Genomics Laboratory (CRTP)

Daniel Soppet, Ph.D., Leidos
Frederick National Laboratory
Phone: 301-228-4447
Fax: 1-846-6100
 
To request full service microarray studies through the CRTP, you must submit a request for a cost estimate through the NCI at Frederick Accession System (NAS): https://ncifrederick.cancer.gov/services/accessioning/. The Core staff will apply OSTR Subsidy (25%) toward the total cost of the request.  DO NOT click on the "Subsidy Request Form" button above.

Gene Editing Resources (Eligible for 33% OSTR Subsidy)

Life Technologies/Applied Biosystems

Christopher Brown, Sr. Sales Representative, Instruments Gene Expression and MicroRNA Quantitation
5781 Van Allen Way
Carlsbad, CA 92008
T: 1-800-327-3002
Cell: 703-967-0586
VM: 1-800-248-0281, x7215

Dharmacon/Thermo Fisher Scientific

Doreen Dyer, Molecular Biology Solutions
Thermo Fisher Scientific
Phone: 301-204-1306

Qiagen

Jeffrey Durocher, Territory Sales Representative QIAGEN Inc.
19300 Germantown Road
Germantown, MD 20874
Phone: 240-449-5109

Sigma-Aldrich

Jamie Newton, Research Science Specialist
Phone: 301-802-8273
YFG Search Engine: sigma.com/yfg
 
Price List:
 
siRNA: $75/duplex (for 10 nmol, standard purification)
 
shRNA:
 
Glycerol: $150/ clone or $60/clone for a set of 5
DNA: $270/clone or $108/clone for a set of 5
Lentiviral Particles: $297.50/clone or $119/clone for a set of 5

System Biosciences

Jacob Lesnik, Associate Marketing Manager
1616 North Shoreline Blvd.
Mountainview, CA 94043
Phone: 888-2666-5066 ext. 102

Blue Heron Biotechnology, Inc.

22310 20th Avenue SE #100
Bothell, WA 98021 USA
Phone:425.368.5000
Email: sales@blueheronbio.com

Genome Mapping (Eligible for 50% OSTR Subsidy)

BioNano Genomics

Why Build a Genome Map?

Genome Maps Defined

Traditionally, generating a whole-genome physical or genetic map has been one of the first steps in exploring genomes. Long-range information is crucial to the accurate understanding of relationships between functional elements in the genome and making sense of more detailed follow-on experiments.

Many current high-throughput genomic technologies start by fragmenting and amplifying DNA. This necessity often sacrifices vital long-range connectivity, causing researchers to miss many structural variants, including rearrangements, inversions and copy-number variants, which lead to inaccurately sized gaps.

Genome maps can contribute greatly to improving contiguity, accurately identifying gaps and revealing missed structural variation, even after a substantial amount of sequencing has been conducted. To achieve higher-quality genome analysis and comprehensive views of variation, a complete genome map is essential.

BioNano Genomics Representative
Jeff Robinson

Regional Business Manager, Mid-Atlantic NA
BioNano Genomics, Inc
cell: 770-608-9666
www.bionanogenomics.com
www.bionanogenomics.com/our-technology/publications

High-Content Imaging

High-Throughput Imaging Facility

Gianluca Pegoraro, Ph.D.
location: Building 41, Bethesda
 
Subsidies towards smaller, pilot projects through the HiTIF can be requested through the OSTR Subsidy website, and are eligible for up to 50% subsidy.  Subsidies for larger projects will be considered through the RRS (Resource Request System).  When logged into the RRS select "OSTR Technology Supplement." 

Metabolomic Screening

Metabolon

John Luster
Metabolon, Inc.
jluster@metabolon.com
919-627-2435

Human Metabolome Technologies

Tsutomu (Tom) Hoshiba
President
24 Denby Rd., Suite 217
Boston, MA 02134
Phone: (617) 987-0554

Microbiome Profiling

CIP Microbiome and Genetics Core

MiSeq/NextSeq500 Sequencing (Eligible for 50% OSTR Subsidy)

CCR Genomics Core (MiSeq/NextSeq500 Operations)

Valery Bliskovsky
location: Bethesda
 
Please contact Val Bliskovsky at bliskovv@mail.nih.gov for project consultation and cost estimates.  Val will provide guidance in terms of amount of available OSTR subsidy.  Projects may be eligible for up to 50% subsidy.

Genomics Laboratory (CRTP)

Daniel Soppet, Ph.D., Leidos
Frederick National Laboratory
Phone: 301-228-4447
Fax: 1-846-6100
 
To request full service microarray studies through the CRTP, you must submit a request for a cost estimate through the NCI at Frederick Accession System (NAS): https://ncifrederick.cancer.gov/services/accessioning/. The Core staff will apply OSTR Subsidy (25%) toward the total cost of the request.  DO NOT click on the "Subsidy Request Form" button above.

Nanoscale Protein Analysis (Eligible for 50% OSTR Subsidy)

Automated charge-based and size-based capillary immunoassay analysis using the Peggy from Protein Simple.

Collaborative Protein Technology Resource

Jessie Chen
 
Subsidy requests must be submitted through the OSTR Technology Program website.  Projects are eligible for 50% subsidy on capillaries.  Please contact Jessie Chen to discuss projects and request a cost estimate.

Next Generation Sequencing

CCR Genomics Core (MiSeq/NextSeq500 Operations)

Valery Bliskovsky
location: Bethesda
 
Please contact Val Bliskovsky at bliskovv@mail.nih.gov for project consultation and cost estimates.  Val will provide guidance in terms of amount of available OSTR subsidy.  Projects may be eligible for up to 50% subsidy.

CCR Sequencing Facility

Bao Tran, Director, CCR Sequencing Facility
Location: Advanced Technology Research Facility, Frederick, MD
 
Exome capture and MiSeq sequencing projects are eligible for OSTR subsidy.  To request subsidy, a project request must be submitted to the Core Services Accession System (CSAS).  Subsidy for other sequencing projects at the SF is factored in to the total cost estimate provided by the core through CSAS.  To submit a sequencing project to the SF, proposals must be submitted through:  https://ostr.cancer.gov/sequence/request

Protein - Protein Interaction Screens

For more information about the CRTP protein-protein interaction screening services, please visit the OSTR website page describing Proteins and Proteomics.

Amount of OSTR subsidy is project dependent.  Up to 50% subsidy may be available.  To request services, please visit the Core Service Accession System (CSAS)

Protein Array Immunoassays (Eligible for 50% OSTR Subsidy)

Meso Scale Discovery

Dennis G. Holloway
Regional Director
Meso Scale Discovery
 
Mobile: 908.896.4514
Office: 908.575.2789

Single-Cell Isolation (Eligible for 50% OSTR Subsidy)

The OSTR has invested in several new technologies for the isolation and analysis of single/rare cells from heterogeneous tissues and cell lines.  These technologies are being made available through centralized resources.  Please contact the individuals listed below to obtain additional information.

Fluidigm

The Fluidigm C1™ Single-Cell Auto Prep System is now available to CCR investigators through the CCR Genomics Core in Building 37, Bethesda.  Please contact Liz Conner (connerl@dc37a.nci.nih.gov) to schedule training and access.  Downstream genomic analysis is available through the MiSeq core in Building 37 and the CCR Sequencing Facility in Frederick, while quantitative PCR using the Biomark HD System is available through the Genomics Technology Lab (GTL) in Frederick.  Fluidigm C1 reagents and Fluidigm Biomark services through GTL are eligible for 50% OSTR subsidy. 

Contact either David Goldstein (goldsted@mail.nih.gov) or Mariam Malik (malikm@mail.nih.gov) if you have questions.

Silicon Biosystems

Silicon Biosystems has combined the ability to manipulate individual cells using DEP technology with high quality image-based cell selection to create the DEPArray™ System. This automated platform enables users to identify and recover specific individual cells of interest from complex, heterogeneous samples.

Teresa Alberobello, Ph.D.
anna.alberobello@nih.gov
Building 37, Room 3035

 

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